I have had to go gluten free as has my middle DD. Celiacs disease runs in the family, although I was only aware of one relative with it so it never really occured to me. For years I had been having several health issues- exhausted, achy, creaky joints, digestive issues, etc. The drs couldn't figure it out and I actually had 3 different ones suggest antidepressants and seeing a psychiatrist. When my DD started having problems I had her try cutting gluten too. I never had it diagnosed by a physician but I have no doubt that it was the gluten. Once I went gf all my symptoms went away or became much more managable. The only time I deal with some of them is if I eat something I should not. The hard part for me has been identifying it in other foods besides the obvious.